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Breast Cancer Patients Could Benefit From Fewer Radiotherapy Treatments

June 22, 2011 | Author: | Posted in Breast Cancer

Breast cancers Patients May need Fewer Radiotherapy Treatments

A significant new medical trial coordinated because of the Institute of Cancer Research (ICR) will determine whether people informed they have cancer of the breast may need receiving fewer radiotherapy treatments versus current UK standard.

British women told they have early cancer of the breast tend to be treated with radiotherapy, usually in 15 treatments delivered more than a three-week period. This became adopted in 2008 reacting with an earlier study led by the ICR that found it was as effective and safe because the five-week, 25 treatment international standard*.

However, there’s some evidence to advise that even fewer treatments may just be as effective – or possibly more potent. The latest trial of four years old,000 men and women will compare the united kingdom standard three-week treatment regimen with two separate one-week schedules of slightly different doses.

“If an one-week treatment schedule is proved to be as or more effective as opposed to UK standard three-week schedule, there’d become a variety of benefits for patients and the health service,” says trial Chief Investigator Professor John Yarnold from the ICR along with the Royal Marsden NHS Foundation Trust. “For example, it would mean less travelling and fewer hospital visits. It would also take back radiotherapy staff and equipment, this means newly-diagnosed patients would be able to start treatment with less delay. Faster access and shorter schedules may even have the treatment better. ”

The Phase III, randomised, controlled trial, called FAST-FORWARD, involves a minimum of 25 radiotherapy centres and will also be coordinated because of the ICR’s Clinical Trials and Statistics Unit. Many experts have funded ?2.9 million in the NIHR HTA programme.

Individuals in the test groups will get five radiotherapy treatments in one week. Every individual daily dose will be more than the UK standard though the overall dose is going to be lower. The trial begins in September 2011 and turn into conducted over 20 years as side effects from radiotherapy can continue for many years after treatment. The trial is primarily examining rates of relapse, but may also assess radiotherapy uncomfortable side effects, quality lifestyle and health economics.

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